38 Round zero.1% of the circumstances are familial types of autosomal (not intercourse-linked ) dominant inheritance, which have an onset before age 65. 39 This type of the illness is called early onset familial Alzheimer’s disease Most of autosomal dominant familial AD may be attributed to mutations in one in all three genes: those Dog paws that’s my child shirt encoding amyloid precursor protein (APP) and presenilins 1 and 2. forty Most mutations in the APP and presenilin genes increase the production of a small protein referred to as Aβ forty two,
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