“I imagine this exhibits beyond a shadow of a doubt that amyloid beta and tau are both prions, and that Alzheimer’s disease is a double-prion dysfunction in which these two rogue proteins together destroy the mind,” Welcome to the jungle predator shirt said Stanley Prusiner, MD, the study’s senior author and director of the UCSF Institute for Neurodegenerative Ailments, part of the UCSF Weill Institute for Neurosciences. Utilizing novel laboratory exams, the researchers had been in a position to detect and measure particular, self-propagating prion forms of the proteins amyloid beta (A-β) and tau in postmortem brain tissue of 75 Alzheimer’s patients.
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