Canine hip dysplasia (CHD) is an orthopedic condition resulting from abnormal development of the hip joint and surrounding tissue causing the instability and partial dislocation of the hip joint, resulting in pain, inflammation, lameness, and potentially osteoarthritis of the joint.German shepherds are genetically predisposed to CHD and the University of Veterinary Medicine in Germany found its prevalence estimated to be approximately 35% of cases associated with the disorder.
Osteoarthritis is one of the main contributors of musculoskeletal pain and disabilities that commonly affect German shepherds. Mechanical stress, oxidative damage and inflammatory mediators combine to induce the gradual degeneration of the articular cartilage in the joint, resulting in reduced muscle mass, pain, and locomotion .
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